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Medical Expertise

Dr. Sebastian Brandner
Dr. Sebastian Brandner. Brain tumor neuropathology expert. Biography. 0
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1. Dr. Sebastian Brandner. Brain tumor neuropathology expert. Biography. 0

Dr. Sebastian Brandner, MD, explains how molecular diagnostics revolutionize brain tumor classification. The Chair of Neuropathology at University College London details his pioneering research on...

How to diagnose brain tumor type? Neurooncology expert explains. Part 1. 1
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2. How to diagnose brain tumor type? Neurooncology expert explains. Part 1. 1

Dr. Sebastian Brandner, MD, explains the step-by-step process of diagnosing brain tumor types, from initial tissue examination to advanced molecular testing. The diagnostic journey begins...

How to diagnose brain tumor type? Neurooncology expert explains. Part 2. 2
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3. How to diagnose brain tumor type? Neurooncology expert explains. Part 2. 2

Dr. Sebastian Brandner, MD, explains how multidisciplinary teams combine molecular diagnostics, imaging, and clinical expertise to accurately diagnose brain tumor types and create personalized treatment...

Brain tumors are diagnosed more often today? 3
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4. Brain tumors are diagnosed more often today? 3

Dr. Sebastian Brandner, MD, examines why brain tumor diagnoses have risen approximately 25% over the past 25 years, exploring whether this reflects true increased incidence...

Astrocytoma or Oligodendroglioma? Precise diagnosis of brain tumors. 4
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5. Astrocytoma or Oligodendroglioma? Precise diagnosis of brain tumors. 4

Dr. Cairncross identified simultaneous loss of chromosome arms 1p and 19q as a hallmark of oligodendroglioma.

Glioblastoma multiforme (GBM). Precise molecular diagnosis. 5
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6. Glioblastoma multiforme (GBM). Precise molecular diagnosis. 5

Dr. Sebastian Brandner, MD, explains how molecular testing for MGMT promoter methylation improves glioblastoma multiforme (GBM) diagnosis and treatment. The epigenetic test predicts response to...

Precise diagnosis of brain tumors. Meningioma, astrocytoma, glioblastoma. 6
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7. Precise diagnosis of brain tumors. Meningioma, astrocytoma, glioblastoma. 6

Dr. Sebastian Brandner, MD, explains how molecular diagnostics revolutionize brain tumor diagnosis and treatment. He details the critical role of IDH mutation testing in gliomas...

ā€˜Fingerprinting brain tumors’. Brain cancer molecular diagnosis. 7
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8. ā€˜Fingerprinting brain tumors’. Brain cancer molecular diagnosis. 7

Dr. Sebastian Brandner, MD, explains how advanced molecular diagnostics like methylation profiling and chromosomal analysis create precise "fingerprints" for brain tumor diagnosis, enabling targeted treatment...

ā€˜Glioblastoma in the making’. Genetic tests predict brain tumor prognosis. Clinical case. 8
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9. ā€˜Glioblastoma in the making’. Genetic tests predict brain tumor prognosis. Clinical case. 8

Dr. Sebastian Brandner, MD, explains how advanced genetic testing detects early-stage glioblastoma when traditional pathology appears benign, enabling earlier aggressive treatment for better brain cancer...

Brain tumors and stem cells. How stem cells become brain cancer. 9
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10. Brain tumors and stem cells. How stem cells become brain cancer. 9

Dr. Sebastian Brandner, MD, explains how brain stem cells can transform into aggressive brain tumors like glioblastoma multiforme (GBM). He discusses the historical evidence, modern...

Can dementia be transmitted? Alzheimer’s disease and Creutzfeldt-Jakob disease. Part 1. 10
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11. Can dementia be transmitted? Alzheimer’s disease and Creutzfeldt-Jakob disease. Part 1. 10

Dr. Sebastian Brandner, MD, explains how Creutzfeldt-Jakob disease (CJD) shares protein misfolding mechanisms with Alzheimer's and Parkinson's, while having unique transmissibility between humans and species....

Alzheimer’s disease cannot be transmitted? But Cerebral Amyloid Angiopathy dementia can be transmitted. Part 2. 11
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12. Alzheimer’s disease cannot be transmitted? But Cerebral Amyloid Angiopathy dementia can be transmitted. Part 2. 11

Dr. Sebastian Brandner, MD, explains how certain dementia-causing proteins can be transmitted through medical procedures. While Alzheimer's disease itself isn't contagious, its amyloid beta proteins...

Alzheimer’s disease and Creutzfeldt-Jakob disease. What is similar? 12
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13. Alzheimer’s disease and Creutzfeldt-Jakob disease. What is similar? 12

Dr. Sebastian Brandner, MD, explains the striking similarities between Alzheimer's disease and Creutzfeldt-Jakob disease (CJD), including their spontaneous development in 95% of cases and potential...

Leading brain tumor diagnosis expert. What motivates him in work and in life? 13
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14. Leading brain tumor diagnosis expert. What motivates him in work and in life? 13

Dr. Sebastian Brandner, MD, explains how complex brain tumor cases and unsolved diagnostic challenges drive his clinical and research work at a major academic medical...